Description

N-(9-Fluorenylmethoxycarbonyl)-L-Alanine is a protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block, enabling the controlled and sequential assembly of complex peptides and proteins in research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the biotechnology, pharmaceutical, and academic sectors for the production of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental Fmoc-protected amino acid for the stepwise construction of custom peptides.
• Pharmaceutical Intermediates: Key raw material in the synthesis of active pharmaceutical ingredients (APIs) for peptide-based drugs.
• Bioconjugation: Used to introduce alanine residues or specific functional handles into biomolecules like proteins and antibodies.
• Research & Development: Essential reagent in academic and industrial labs for studying protein structure, function, and peptide chemistry.
• Combinatorial Chemistry: Building block for creating diverse peptide libraries used in drug discovery and screening.
• Proteomics and Biochemical Studies: Employed in the synthesis of substrates, inhibitors, and standards for enzymatic assays and metabolic research.

Basic Information

Product Name	N-(9-Fluorenylmethoxycarbonyl)-L-Alanine
CAS No.	207291-76-7
Molecular Formula	C18H17NO4
Molecular Weight	311.33 g/mol
Synonyms	Fmoc-L-Alanine; Fmoc-Ala-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]propanoic acid; N-(9-Fluorenylmethoxycarbonyl)alanine; Fmoc-Ala; L-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-; NSC 334280
EINECS	Contact for details

Quality Control

Our N-(9-Fluorenylmethoxycarbonyl)-L-Alanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.