Description

α-Chloro-2-(Trifluoromethyl)Benzyl is a versatile and high-value fluorinated benzyl halide building block. This compound is critical for introducing the (trifluoromethyl)benzyl moiety into complex molecular architectures, a key strategy in modern synthetic chemistry. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethylated aromatic system to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the CF3 group enhances biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in organic synthesis for creating novel chiral ligands or organocatalysts containing the benzyl chloride handle for further modification.
• Chemical Research & Development: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in both industrial and academic settings.

Basic Information

Product Name	α-Chloro-2-(Trifluoromethyl)Benzyl
CAS No.	206986-86-9
Molecular Formula	C8H6ClF3
Molecular Weight	194.58 g/mol
Synonyms	2-(Trifluoromethyl)benzyl chloride; α-Chloro-2-(trifluoromethyl)toluene; 1-(Chloromethyl)-2-(trifluoromethyl)benzene; (2-(Trifluoromethyl)phenyl)methyl chloride; 2-(Trifluoromethyl)benzylchloride; o-Trifluoromethylbenzyl chloride
EINECS	Contact for details

Quality Control

Our α-Chloro-2-(Trifluoromethyl)Benzyl is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature and reactivity, it is recommended to use under an inert atmosphere for extended storage periods.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.