Description

2-Chloro-3,5-Difluorophenol is a halogenated phenol derivative serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the strategic positioning of chlorine and fluorine atoms on the aromatic ring, which allows for precise modification of electronic and steric properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Building block for herbicides, fungicides, and pesticides, where the difluorophenol moiety contributes to biological activity and metabolic stability.
• Liquid Crystal Materials: Used in the synthesis of fluorinated compounds for electronic display applications.
• Polymer Chemistry: Monomer or modifier for engineering plastics and high-performance polymers.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, etherification, and as a protecting group precursor in complex multi-step syntheses.

Basic Information

Product Name	2-Chloro-3,5-Difluorophenol
CAS No.	206986-81-4
Molecular Formula	C6H3ClF2O
Molecular Weight	164.54 g/mol
Synonyms	3,5-Difluoro-2-chlorophenol; 2-Chloro-3,5-difluorophenol; Phenol, 2-chloro-3,5-difluoro-; 2-Chloro-3,5-difluoro phenol
EINECS	Contact for details

Quality Control

Our 2-Chloro-3,5-Difluorophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.