Description

Pyrimidine, 2-(Chloromethyl)-, 1-Oxide (9Ci) is a specialized heterocyclic building block characterized by its reactive chloromethyl and N-oxide functional groups. This compound is of significant value in advanced organic synthesis, particularly for constructing complex molecular architectures in pharmaceutical and agrochemical research. It serves as a key intermediate for medicinal chemists and process development scientists working on novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides.
• Chemical Research & Development: Serves as a versatile reagent for constructing complex heterocyclic compounds in academic and industrial R&D labs.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and functional materials.
• Cross-Coupling Reactions: The reactive chloromethyl group makes it suitable for further functionalization via various metal-catalyzed reactions.

Basic Information

Product Name	Pyrimidine, 2-(Chloromethyl)-, 1-Oxide (9Ci)
CAS No.	206882-35-1
Molecular Formula	C5H5ClN2O
Molecular Weight	144.56 g/mol
Synonyms	2-(Chloromethyl)pyrimidine 1-Oxide; 2-(Chloromethyl)pyrimidine N-Oxide; Pyrimidine, 2-(chloromethyl)-, 1-oxide; 2-Chloromethylpyrimidine 1-Oxide; 2-Pyrimidinylmethyl chloride 1-Oxide; 206882-35-1; (Chloromethyl)pyrimidine N-Oxide
EINECS	Contact for details

Quality Control

Our Pyrimidine, 2-(Chloromethyl)-, 1-Oxide (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and test results are provided with every shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.