Description

Fmoc-Phe-Lys(Boc)-Pab CAS NO 206133-42-8 is a protected tripeptide building block specifically designed for solid-phase peptide synthesis (SPPS). This compound is critical for the efficient and high-fidelity assembly of complex peptide sequences, particularly in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the biotechnology and pharmaceutical industries for the production of therapeutic peptides, peptide hormones, and investigative biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the stepwise construction of custom peptide chains in automated synthesizers.
• Pharmaceutical R&D: Used in the discovery and development of novel peptide-based therapeutics, including anticancer agents and hormone analogs.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify bioactive peptide leads.
• Antibody-Drug Conjugate (ADC) Development: Can be incorporated into the design of peptide linkers for targeted drug delivery systems.
• Academic Research: Fundamental studies in biochemistry, enzymology, and molecular biology involving peptide-protein interactions.

Basic Information

Item	Detail
Product Name	Fmoc-Phe-Lys(Boc)-Pab
CAS No.	206133-42-8
Molecular Formula	C46H54N6O8
Molecular Weight	818.97 g/mol
Synonyms	Fmoc-Phe-Lys(Boc)-Pab-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanyl-N6-[(1,1-dimethylethoxy)carbonyl]-L-lysyl-4-(aminomethyl)benzoic acid; Fmoc-Phe-Lys(Boc)-PAB; Fmoc-Phenylalanyl-Nε-Boc-Lysyl-PAB; PAB Resin Linker Precursor; Fmoc-L-Phe-L-Lys(Boc)-PAB; 4-[[[2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-phenyl-1-oxopropyl][[6-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxo-2-hexyl]amino]methyl]benzoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-Phe-Lys(Boc)-Pab is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -15°C. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a dry environment before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.