Description

3-Amino-5-Methyl-1,3-Dihydro-Benzo[E][1,4]Diazepin-2-One is a high-purity, specialized benzodiazepine derivative serving as a critical advanced intermediate in modern pharmaceutical synthesis. Its value lies in providing a structurally complex and functionalized core for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and development chemists and production units in the pharmaceutical and biotechnology sectors seeking to build complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzodiazepine-based therapeutic agents and other bioactive molecules.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce the 1,4-diazepin-2-one scaffold into more complex molecular architectures.
• API Development: Serves as a precursor in the development and scale-up processes for new Active Pharmaceutical Ingredients.

Basic Information

Item	Detail
Product Name	3-Amino-5-Methyl-1,3-Dihydro-Benzo[E][1,4]Diazepin-2-One
CAS No.	205989-36-2
Molecular Formula	C11H11N3O
Molecular Weight	201.23 g/mol
Synonyms	3-Amino-5-methyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one; 5-Methyl-3-amino-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 3-Amino-5-methyl-1H-1,4-benzodiazepin-2(3H)-one; 205989-36-2; Benzo[e][1,4]diazepin-2-one, 3-amino-5-methyl-1,3-dihydro-; 3-Amino-5-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Methyl-1,3-Dihydro-Benzo[E][1,4]Diazepin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling. Certificates of Analysis (COA) documenting identity, purity, and related substances are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.