Description

Ethanone, 1-(2-Amino-6-Fluorophenyl)-2,2,2-Trifluoro- (9Ci) is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of an amino group and a trifluoroacetyl moiety on a fluorinated benzene ring, enabling precise molecular modifications. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring fluorinated motifs.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity, stability, and metabolic properties.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and advanced organic electronic materials that benefit from its unique electronic properties.
• Fluorine Chemistry Studies: An important reagent for investigating structure-activity relationships (SAR) and the effects of polyfluorination on molecular reactivity and physical characteristics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring high-purity, complex fluorinated intermediates.

Basic Information

Product Name	Ethanone, 1-(2-Amino-6-Fluorophenyl)-2,2,2-Trifluoro- (9Ci)
CAS No.	205756-56-5
Molecular Formula	C8H5F4NO
Molecular Weight	207.13 g/mol
Synonyms	2-Amino-6-fluorophenyl trifluoromethyl ketone; 1-(2-Amino-6-fluorophenyl)-2,2,2-trifluoroethanone; 2-Amino-α,α,α-trifluoro-6-fluoroacetophenone; 2'-Amino-6'-fluoro-2,2,2-trifluoroacetophenone; 6-Fluoro-2-aminophenyl trifluoromethyl ketone; (2-Amino-6-fluorophenyl)(trifluoromethyl)methanone; Trifluoro(2-amino-6-fluorophenyl)methanone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2-Amino-6-Fluorophenyl)-2,2,2-Trifluoro- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.