Description

Orexin A (Bovine, Human, Mouse, Rat) is a potent neuropeptide hormone that plays a critical role in regulating arousal, wakefulness, and appetite. This high-purity peptide is essential for advanced neuroscience and metabolic research, providing a reliable tool for studying sleep disorders and energy homeostasis. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies developing novel therapeutics.

Application

• Neuroscience Research: Fundamental studies on sleep/wake cycles, narcolepsy, and arousal mechanisms.
• Metabolic Disorder Studies: Investigation of orexin's role in feeding behavior, obesity, and energy balance.
• Drug Discovery & Development: Screening and validation of orexin receptor (OX1R/OX2R) agonists and antagonists for therapeutic candidates.
• In Vitro & In Vivo Assays: Used as a reference standard in cell-based assays and animal model studies.
• Biochemical Reagent: A key reagent for receptor binding studies and signal transduction pathway analysis.
• Academic & Clinical Research: Supports peer-reviewed research in physiology, pharmacology, and neurology.

Basic Information

Product Name	Orexin A (Bovine, Human, Mouse, Rat)
CAS No.	205640-90-0
Molecular Formula	C152H246N50O48S2
Molecular Weight	3561.9 g/mol
Synonyms	Hypocretin-1; Hypocretin Neuropeptide Precursor 1; Orexin-1; Orexin-A; OXA; HCRT; PPOX; Prepro-orexin; Hypocretin (human); Hypocretin-1 (33-64) (human, bovine, mouse, rat)
EINECS	Contact for details

Quality Control

Our Orexin A is manufactured under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content. We adhere to GMP principles for research-grade peptides, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider aliquoting to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.