Description

2H-1-Benzopyran-2-Carboxamide, n-(6-Amino-1,2,3,4-Tetrahydro-3-Methyl-2,4-Dioxo-1-Phenyl-5-Pyrimidinyl)-3,4-Dihydro-6-Hydroxy-2,5,7,8-Tetramethyl-, (2S)- is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its complex molecular architecture, which serves as a key building block in the synthesis of novel therapeutic agents. It is primarily sought after by R&D laboratories and fine chemical manufacturers in the pharmaceutical and biotechnology sectors for developing new drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug molecules targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold or a derivatization starting point for structure-activity relationship (SAR) studies in drug discovery programs.
• API Development: Serves as a key chiral intermediate in the development and process optimization of new Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Potential use as a tool compound or a ligand in biochemical assays and enzyme inhibition studies.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.

Basic Information

Product Name	2H-1-Benzopyran-2-Carboxamide, n-(6-Amino-1,2,3,4-Tetrahydro-3-Methyl-2,4-Dioxo-1-Phenyl-5-Pyrimidinyl)-3,4-Dihydro-6-Hydroxy-2,5,7,8-Tetramethyl-, (2S)-
CAS No.	204980-81-4
Molecular Formula	C25H28N4O5
Molecular Weight	464.52 g/mol
Synonyms	(2S)-N-(6-Amino-1,2,3,4-tetrahydro-3-methyl-2,4-dioxo-1-phenyl-5-pyrimidinyl)-3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxamide; (S)-Troloxamide Pyrimidine Derivative; 2H-1-Benzopyran-2-carboxamide, N-(6-amino-1,2,3,4-tetrahydro-3-methyl-2,4-dioxo-1-phenyl-5-pyrimidinyl)-3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (2S)-; CAS 204980-81-4
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.