Description

Fmoc-D, L-Phe(4-C(O)Nh2) is a protected amino acid derivative used in solid-phase peptide synthesis (SPPS). This compound matters for its role as a key building block in the production of complex peptides and peptidomimetics, enabling precise control over molecular architecture. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery, development of therapeutic peptides, and biochemical research.

Application

• Solid-Phase Peptide Synthesis (SPPS): A crucial protected amino acid building block for the automated synthesis of custom peptides.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based therapeutics and drug candidates.
• Bioconjugation: Serves as a modified amino acid for creating labeled peptides or peptide-protein conjugates for diagnostic and research applications.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify bioactive compounds.
• Academic & Biochemical Research: A fundamental reagent for studying protein structure-function relationships and enzyme-substrate interactions.
• Production of Modified Peptides: Enables the incorporation of specific, functionalized side chains to alter peptide stability, activity, or solubility.

Basic Information

Product Name	Fmoc-D, L-Phe(4-C(O)Nh2)
CAS No.	204716-17-6
Molecular Formula	C25H22N2O5
Molecular Weight	430.46 g/mol
Synonyms	Fmoc-4-Amidophenylalanine; Fmoc-Phe(4-CONH2)-OH; N-(9-Fluorenylmethoxycarbonyl)-4-carbamoylphenylalanine; Fmoc-DL-4-Amidophenylalanine; Nα-Fmoc-4-amido-L-phenylalanine; Fmoc-Phe(4-NH2CO)-OH; Fmoc-Phe(p-CONH2)-OH; (RS)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-carbamoylphenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-D, L-Phe(4-C(O)Nh2) is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each lot undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and specific impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.