Description

Fmoc-D-Tyr(3,5-Br2)-Oh is a protected, non-natural amino acid derivative specifically engineered for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring the precise incorporation of a brominated tyrosine residue with D-configuration into peptide chains, enabling the study of structure-activity relationships and the development of novel bioactive molecules. It is an essential building block for pharmaceutical R&D, particularly in the development of peptide-based therapeutics, diagnostic agents, and chemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated synthesis of complex peptides containing brominated tyrosine.
• Pharmaceutical Research: Used in the discovery and development of novel peptide drugs, hormones, and enzyme inhibitors.
• Chemical Biology & Proteomics: Enables site-specific labeling and modification of peptides for studying protein-protein interactions and cellular processes.
• Agrochemical Development: Serves as a precursor in the synthesis of bioactive peptide analogs for crop protection.
• Material Science: A building block for creating specialized peptide-based polymers and biomaterials.
• Academic Research: Fundamental reagent for studying peptide conformation, stability, and receptor binding.

Basic Information

Product Name	Fmoc-D-Tyr(3,5-Br2)-Oh
CAS No.	204693-22-1
Molecular Formula	C₂₄H₁₉Br₂NO₅
Molecular Weight	585.22 g/mol
Synonyms	Fmoc-D-3,5-Dibromotyrosine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3,5-dibromo-D-tyrosine; Fmoc-D-Tyr(Br2)-OH; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3,5-dibromo-4-hydroxyphenyl)propanoic acid; Fmoc-D-3,5-dibromotyrosine-OH; N-Fmoc-3,5-dibromo-D-tyrosine; Fmoc-D-Tyr(3,5-diBr)-OH; Fmoc-D-3,5-Dibromo-Tyr-OH
EINECS	Contact for details

Quality Control

Our Fmoc-D-Tyr(3,5-Br2)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm D-configuration, and identity confirmation by NMR and mass spectrometry. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% D-isomer
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.