Description

L-Tryprophan-15N2 95% Cp 95 Atom% 15N CAS NO 204634-20-8 is a stable isotope-labeled analog of the essential amino acid L-Tryptophan, featuring two nitrogen-15 atoms at high isotopic enrichment. This product is critical for advanced research and analytical applications where precise metabolic tracing and quantification are required. It is primarily utilized by pharmaceutical researchers, academic institutions, and diagnostic developers in metabolomics, pharmacokinetic studies, and as an internal standard for mass spectrometry.

Application

• Mass Spectrometry Internal Standard: Used as a quantitative reference standard in LC-MS and GC-MS analyses for accurate measurement of endogenous L-Tryptophan levels in biological samples.
• Metabolic Pathway Tracing: Enables the study of tryptophan metabolism, including the kynurenine and serotonin pathways, in cell culture and in vivo models.
• Pharmaceutical Research & Development: Supports drug discovery and development efforts for compounds targeting neurological disorders, immune modulation, and cancer.
• Clinical Diagnostics: Serves as a key component in the development of assays for diagnosing metabolic diseases related to amino acid imbalances.
• Nutritional Science Research: Used in studies investigating protein metabolism, amino acid requirements, and the impact of diet on metabolic health.
• Isotope Dilution Analysis (IDA): Provides high accuracy and precision in the quantification of L-Tryptophan in complex matrices like food, plasma, and tissue homogenates.

Basic Information

Item	Details
Product Name	L-Tryprophan-15N2 95% Cp 95 Atom% 15N
CAS No.	204634-20-8
Molecular Formula	C11H1215N2O2
Molecular Weight	Contact for details
Synonyms	(2S)-2-Amino-3-(1H-indol-3-yl)propanoic-15N2 acid; L-Tryptophan-15N2; Tryptophan-15N2; L-TRP-15N2; 1H-Indole-3-propanoic acid, α-amino-, (S)-, labeled with nitrogen-15; Stable Isotope Labeled L-Tryptophan; L-Tryptophan (indole-15N2)
EINECS	Contact for details

Quality Control

Our L-Tryprophan-15N2 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the specified 95% chemical purity and 95 atom% 15N isotopic enrichment. Certificates of Analysis (COA) are provided, detailing results from HPLC, NMR, and mass spectrometry analyses for identity, purity, and isotopic abundance verification.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isotopic Enrichment (MS)	≥ 95 atom% 15N
Chemical Purity	≥ 95%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.