Description

Arg34-Glp-1(7-37) is a synthetic peptide analog of glucagon-like peptide-1 (GLP-1), a key incretin hormone involved in glucose metabolism. This high-purity compound is critical for advanced pharmaceutical research and development, particularly in the study of diabetes and metabolic disorders. It serves as an essential reference standard and active pharmaceutical ingredient (API) intermediate for researchers and manufacturers in the biopharmaceutical sector.

Application

• Pharmaceutical R&D: Primary use as a reference standard and lead compound in the development of novel GLP-1 receptor agonists for Type 2 diabetes and obesity treatments.
• Metabolic Research: A vital tool for in vitro and in vivo studies investigating insulin secretion, β-cell function, and appetite regulation pathways.
• API Intermediate: Serves as a key building block in the multi-step synthesis of longer-acting or modified GLP-1 analog therapeutics.
• Biochemical Assay Development: Used to calibrate assays, validate analytical methods (HPLC, LC-MS), and assess receptor binding affinity.
• Quality Control: Acts as a system suitability standard in the quality control laboratories of peptide API manufacturers.

Basic Information

Product Name	Arg34-Glp-1(7-37)
CAS No.	204521-68-6
Molecular Formula	C149H226N40O45
Molecular Weight	3299.7 g/mol
Synonyms	Arg34-GLP-1(7-37); [Arg34]GLP-1(7-37); Glucagon-like peptide 1 (7-37) (human) with Arg at position 34; GLP-1 (7-37) (Arg34); H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; GLP-1 analog; Incretin mimetic peptide
EINECS	Contact for details

Quality Control

Our Arg34-Glp-1(7-37) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and endotoxins, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.