Description

Dl-Lysine-ε-15N Dihydrochloride is a stable, isotopically labeled salt form of the essential amino acid lysine, specifically enriched with the 15N isotope at the ε-amino position. This compound is a critical tool for advanced research in metabolism, protein dynamics, and nutritional studies, providing a non-radioactive tracer for precise quantification and pathway analysis. It is primarily utilized by research institutions, pharmaceutical R&D departments, and analytical laboratories engaged in mass spectrometry, NMR spectroscopy, and stable isotope probing.

Application

• Metabolic Pathway Tracing: Used as a stable isotope-labeled precursor in metabolic flux analysis (MFA) to study amino acid and protein turnover in biological systems.
• Quantitative Proteomics & Mass Spectrometry: Serves as an internal standard for the accurate absolute quantification (AQUA) of proteins and peptides via LC-MS/MS.
• Nutritional Research: Employed in studies investigating lysine utilization, bioavailability, and requirements in humans and animals.
• Pharmaceutical Development: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the incorporation of lysine into biologic therapeutics.
• NMR Spectroscopy: Provides a distinct 15N signal for structural and dynamic studies of proteins and biomolecules.
• Microbial & Plant Physiology: Applied in stable isotope probing (SIP) to trace nitrogen assimilation and metabolism in complex environmental or biological samples.

Basic Information

Product Name	Dl-Lysine-ε-15N Dihydrochloride
CAS No.	204451-46-7
Molecular Formula	C₆H₁₅¹⁵N₂O₂•2HCl
Molecular Weight	Contact for details
Synonyms	DL-Lysine-ε-15N dihydrochloride; (RS)-2,6-Diaminohexanoic-ε-15N acid dihydrochloride; Lysine-ε-15N dihydrochloride (DL); (±)-Lysine-ε-15N dihydrochloride; H-DL-Lys(ε-15N)-OH•2HCl; 15N-Labeled DL-lysine dihydrochloride; 2,6-Diaminocaproic-ε-15N acid dihydrochloride
EINECS	Contact for details

Quality Control

Our Dl-Lysine-ε-15N Dihydrochloride is manufactured under strict quality systems to ensure high isotopic and chemical purity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (Atom % 15N), chemical purity by HPLC, and chiral purity. We adhere to relevant standards for research-grade biochemicals, and custom specifications for GMP or other regulatory frameworks can be discussed.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This material is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % 15N)	≥ 98%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.