Description

4-Hydroxy-2-(Pyridin-4-Yl)-6-(Trifluoromethyl)Pyrimidine is a high-value heterocyclic building block characterized by its pyrimidine core functionalized with a pyridinyl group and a trifluoromethyl substituent. This compound is essential for research and development in advanced organic synthesis, where its unique structure enables the creation of novel molecules with tailored properties. It is primarily sought after by pharmaceutical and agrochemical R&D teams for use as a key intermediate in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine scaffold.
• Material Science: Serves as a precursor for creating specialty chemicals, ligands for catalysis, and advanced organic electronic materials.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and exploring structure-activity relationships (SAR).
• Bioconjugation & Probe Development: Useful for modifying biomolecules or creating fluorescent probes and diagnostic agents due to its reactive sites.

Basic Information

Product Name	4-Hydroxy-2-(Pyridin-4-Yl)-6-(Trifluoromethyl)Pyrimidine
CAS No.	204394-60-5
Molecular Formula	C10H6F3N3O
Molecular Weight	241.17 g/mol
Synonyms	4-Hydroxy-2-(4-pyridinyl)-6-(trifluoromethyl)pyrimidine; 2-(Pyridin-4-yl)-6-(trifluoromethyl)pyrimidin-4-ol; 6-(Trifluoromethyl)-2-(4-pyridinyl)-4-pyrimidinol; 4-Pyrimidinol, 2-(4-pyridinyl)-6-(trifluoromethyl)-; 4-Hydroxy-2-(4-pyridyl)-6-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-2-(Pyridin-4-Yl)-6-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.