Description

Ethyl 4-Chloro-2-Pyridin-4-Ylpyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyrimidine-pyridine heterocyclic structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted small-molecule drugs.
• Agrochemical Research: Used in the development of new herbicides and fungicides due to its bioactive heterocyclic core.
• Chemical Synthesis: Serves as a versatile building block for constructing complex polyheterocyclic compounds in medicinal chemistry.
• Material Science Research: Investigated as a potential monomer or ligand for creating functional organic materials and metal-organic frameworks (MOFs).
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	Ethyl 4-Chloro-2-Pyridin-4-Ylpyrimidine-5-Carboxylate
CAS No.	204394-36-5
Molecular Formula	C12H10ClN3O2
Molecular Weight	263.68 g/mol
Synonyms	Ethyl 4-chloro-2-(pyridin-4-yl)pyrimidine-5-carboxylate; 4-Chloro-2-(4-pyridinyl)-5-pyrimidinecarboxylic acid ethyl ester; 2-(4-Pyridinyl)-4-chloro-5-pyrimidinecarboxylic acid ethyl ester; 204394-36-5; Ethyl 4-chloro-2-(4-pyridyl)pyrimidine-5-carboxylate; 5-Pyrimidinecarboxylic acid, 4-chloro-2-(4-pyridinyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-2-Pyridin-4-Ylpyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.