Description

Osteostatin Amide (Human) CAS NO 204383-55-1 is a synthetic peptide fragment derived from the C-terminal region of parathyroid hormone-related protein (PTHrP). This compound is a critical research tool for investigating bone metabolism and the regulation of osteoclast activity. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on metabolic bone diseases and novel therapeutic development.

Application

• Biomedical Research: Fundamental studies on bone biology, osteoclast differentiation, and bone resorption mechanisms.
• Drug Discovery & Development: Screening and validation of targets for osteoporosis, Paget's disease, and cancer-induced bone metastasis.
• In Vitro & In Vivo Assays: Used as a reference standard or active agent in cell-based assays and animal models of bone disease.
• Mechanistic Studies: Investigating the signaling pathways of PTHrP and its role in calcium homeostasis.
• Peptide Chemistry Research: Serves as a model compound for studying structure-activity relationships (SAR) of bioactive peptide sequences.

Basic Information

Product Name	Osteostatin Amide (Human)
CAS No.	204383-55-1
Molecular Formula	C41H68N14O11
Molecular Weight	909.1 g/mol
Synonyms	PTHrP (107-111) amide (human); [Ala107, Leu111]PTHrP(107-111) amide; hPTHrP(107-111)-NH2; Osteostatin (107-111) amide; PTHrP-derived peptide (107-111); Ala-Val-Leu-Gly-Lys-NH2; AVLGK-NH2
EINECS	Contact for details

Quality Control

Our Osteostatin Amide (Human) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized by advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and content is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.