Description

Boc-Ser-Oh H2O is a protected amino acid derivative, specifically the tert-butoxycarbonyl (Boc) derivative of L-serine hydrate. This compound is a fundamental and high-value building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptide sequences. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require reliable, high-purity intermediates for drug discovery and development.

Application

• Peptide Synthesis: A critical reagent in the stepwise construction of peptides using Fmoc/t-Boc chemistry protocols.
• Pharmaceutical Intermediates: Serves as a key starting material for the synthesis of therapeutic peptides and peptidomimetics.
• Bioconjugation: Used to introduce serine residues with orthogonal protecting groups for site-specific protein and antibody modifications.
• Research & Development: Employed in academic and industrial R&D for exploring new peptide-based drugs, hormones, and diagnostic agents.
• Combinatorial Chemistry: A valuable building block in libraries for high-throughput screening of bioactive compounds.
• Glycopeptide Synthesis: Facilitates the synthesis of peptides containing O-linked glycosylation sites due to the serine side chain.

Basic Information

Product Name	Boc-Ser-Oh H2O
CAS No.	204191-40-2
Molecular Formula	C8H17NO6
Molecular Weight	223.23 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-serine hydrate; Boc-L-serine hydrate; (2S)-2-[(tert-Butoxycarbonyl)amino]-3-hydroxypropanoic acid hydrate; Boc-Ser-OH·H2O; BOC-Ser-OH monohydrate; tert-Butyloxycarbonyl-L-serine hydrate; N-Boc-L-serine hydrate; N-α-Boc-L-serine hydrate
EINECS	Contact for details

Quality Control

Our Boc-Ser-Oh H2O is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identification tests. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.5%
Specific Rotation	[α]20/D: Contact for details
Water Content (KF)	Meets theoretical hydrate value
Heavy Metals	<10 ppm
Residue on Ignition	<0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.