Description

N6,N6-Dimethyl-N2-[(Benzyloxy)Carbonyl]-L-Lysine tert-Butyl Ester is a protected amino acid derivative, specifically a modified lysine building block, essential for advanced organic synthesis. This compound matters because it provides critical orthogonality in peptide synthesis, allowing for the selective deprotection of specific functional groups during complex multi-step reactions. Pharmaceutical researchers and fine chemical manufacturers need it for the development of novel peptide-based therapeutics, diagnostic agents, and other bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled incorporation of modified lysine residues into peptide chains.
• Solution-Phase Peptide Chemistry: Used in the synthesis of complex peptides and peptidomimetics where selective protecting group strategies are required.
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease research.
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins for creating antibody-drug conjugates (ADCs) or diagnostic probes.
• Chemical Biology Research: Employed in the synthesis of tool compounds and probes to study protein-protein interactions and enzyme function.
• Custom Synthesis Services: A high-value starting material for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis.

Basic Information

Product Name	N6,N6-Dimethyl-N2-[(Benzyloxy)Carbonyl]-L-Lysine tert-Butyl Ester
CAS No.	204074-50-0
Molecular Formula	C21H34N2O4
Molecular Weight	378.51 g/mol
Synonyms	Nα-Cbz-Nε,Nε-dimethyl-L-lysine tert-butyl ester; (S)-2-(((Benzyloxy)carbonyl)amino)-6-(dimethylamino)hexanoic acid tert-butyl ester; Boc-Lys(NεMe2)-OH (common mis-assignment, note protecting group difference); Z-Lys(NMe2)-OtBu; N2-[(Benzyloxy)carbonyl]-N6,N6-dimethyl-L-lysine 1,1-dimethylethyl ester; Fmoc-Lys(NεMe2)-OH tert-butyl ester precursor; Protected dimethyllysine derivative
EINECS	Contact for details

Quality Control

Our N6,N6-Dimethyl-N2-[(Benzyloxy)Carbonyl]-L-Lysine tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support projects requiring documentation for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.