Description

1-Methyl-6-(Trifluoromethyl)-2,4(1H,3H)-Pyrimidinedione is a specialized heterocyclic compound featuring a pyrimidinedione core substituted with a methyl and a trifluoromethyl group. This structure is of significant value as a key synthetic intermediate or building block in advanced organic synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, or fungicides where the trifluoromethyl group can enhance biological activity and stability.
• Fine Chemical Production: Serves as a specialized precursor in the manufacture of complex organic compounds for research and industrial applications.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, structure-activity relationship (SAR) studies, and exploring new chemical entities.
• Material Science: Potential use as a monomer or functional additive in the development of specialty polymers or advanced materials.

Basic Information

Product Name	1-Methyl-6-(Trifluoromethyl)-2,4(1H,3H)-Pyrimidinedione
CAS No.	203938-27-6
Molecular Formula	C6H5F3N2O2
Molecular Weight	194.11 g/mol
Synonyms	6-(Trifluoromethyl)-1-methyluracil; 1-Methyl-6-(trifluoromethyl)uracil; 1-Methyl-6-trifluoromethyl-2,4(1H,3H)-pyrimidinedione; 6-Trifluoromethyl-1-methyluracil; 1-Methyl-6-trifluoromethyluracil; 6-(Trifluoromethyl)-1-methyl-2,4(1H,3H)-pyrimidinedione; 1-Methyl-6-(trifluoromethyl)-2,4-dihydroxypyrimidine
EINECS	Contact for details

Quality Control

Our 1-Methyl-6-(Trifluoromethyl)-2,4(1H,3H)-Pyrimidinedione is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.