Description

Ert-Butyl 4-(6-Chloro-2-Methyl-4-Pyrimidinyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily sought after by research institutions and manufacturers in the global pharmaceutical and agrochemical sectors for the development of novel drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug molecules, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Serves as a key scaffold for developing new generation pesticides and herbicides, leveraging its pyrimidine and pyrazine moieties.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex nitrogen-containing heterocycles due to its reactive chloro and ester functional groups.
• Process Chemistry & Scale-Up: Employed in process optimization and kilogram-to-ton scale production for clinical trial material and commercial API manufacturing.
• Contract Manufacturing (CMO/CDMO): Supplied to contract development and manufacturing organizations for custom synthesis projects.

Basic Information

Product Name	Ert-Butyl 4-(6-Chloro-2-Methyl-4-Pyrimidinyl)Tetrahydro-1(2H)-Pyrazinecarboxylate
CAS No.	203519-37-3
Molecular Formula	C14H21ClN4O2
Molecular Weight	312.80 g/mol
Synonyms	tert-Butyl 4-(6-chloro-2-methylpyrimidin-4-yl)piperazine-1-carboxylate; 1-Boc-4-(6-Chloro-2-methyl-4-pyrimidinyl)piperazine; 4-(6-Chloro-2-methyl-4-pyrimidinyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-(6-chloro-2-methylpyrimidin-4-yl)piperazine; BOC-4-(6-Chloro-2-methyl-4-pyrimidinyl)piperazine; 203519-37-3; tert-Butyl 4-(6-chloro-2-methyl-4-pyrimidinyl)-1-piperazinecarboxylate
EINECS	Contact for details

Quality Control

Our Ert-Butyl 4-(6-Chloro-2-Methyl-4-Pyrimidinyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.