Description

4-(Fmoc-2-Aminoethyl)-Benzoic Acid is a high-purity, protected amino acid derivative designed for advanced organic synthesis. This compound is a critical building block for the solid-phase peptide synthesis (SPPS) of complex peptides and peptidomimetics, offering precise control over molecular architecture. It is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced materials science who require reliable, high-quality intermediates for constructing bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected intermediate for the controlled, sequential assembly of custom peptides.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based therapeutics, including hormone analogs and enzyme inhibitors.
• Bioconjugation: Serves as a linker molecule for attaching peptides or other functional groups to surfaces, polymers, or biomolecules via its carboxylic acid moiety.
• Combinatorial Chemistry: Employed in the generation of diverse chemical libraries for high-throughput screening in drug discovery.
• Material Science: A precursor for creating functionalized organic frameworks or smart materials with specific biological activity.
• Academic Research: A fundamental reagent for studying peptide structure-activity relationships and developing new synthetic methodologies.

Basic Information

Product Name	4-(Fmoc-2-Aminoethyl)-Benzoic Acid
CAS No.	203453-80-9
Molecular Formula	C24H21NO4
Molecular Weight	387.43 g/mol
Synonyms	Fmoc-2-Aminoethyl-benzoic Acid; 4-[(9H-Fluoren-9-ylmethoxy)carbonylamino]ethyl]benzoic Acid; 2-{4-[(Fmoc-amino)ethyl]}benzoic Acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-(4-carboxyphenyl)ethylamine; Fmoc-NH-CH2-CH2-C6H4-COOH; 4-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)benzoic Acid; Fmoc-AEEA-OH (common abbreviation); Fmoc-protected AEEA linker
EINECS	Contact for details

Quality Control

Our 4-(Fmoc-2-Aminoethyl)-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.