Description

2,6-Dichloro-9-(1-methylethyl)-9H-purine is a high-purity, substituted purine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical pharmaceutical intermediate for the development of novel therapeutic agents, particularly in antiviral and anticancer research. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the synthesis of complex nucleoside analogs and purine-based small molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nucleoside analog prodrugs and targeted small molecule inhibitors.
• Antiviral Drug Research: Used in the development of potential therapeutic agents against viral infections.
• Oncology Research: Serves as a precursor for compounds being investigated for their anticancer properties.
• Biochemical Tool Compound: Employed in enzymatic studies and as a reference standard in analytical method development.
• Process Chemistry & Scale-up: Utilized in route scouting, optimization, and pilot-scale manufacturing of active pharmaceutical ingredients (APIs).
• Custom Synthesis: Starting material for the preparation of more complex, functionalized purine derivatives for specialized applications.

Basic Information

Product Name	2,6-Dichloro-9-(1-methylethyl)-9H-purine
CAS No.	203436-45-7
Molecular Formula	C9H8Cl2N4
Molecular Weight	243.09 g/mol
Synonyms	2,6-Dichloro-9-isopropylpurine; 9-Isopropyl-2,6-dichloropurine; 2,6-Dichloro-9-(propan-2-yl)-9H-purine; 2,6-Dichloro-9-(1-methylethyl)purine; 2,6-Dichloro-9-isopropyl-9H-purine; NSC 339579; Purine, 2,6-dichloro-9-(1-methylethyl)-
EINECS	Contact for details

Quality Control

Our 2,6-Dichloro-9-(1-methylethyl)-9H-purine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.