Description

Pyr-Phe-Gly-Nh2 CAS NO 203396-25-2 is a synthetic tripeptide derivative, specifically a pyroglutamyl-phenylalanyl-glycinamide. This compound is a high-purity, specialized peptide building block of significant interest in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel therapeutic agents, particularly in the fields of neurobiology and endocrinology.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies and receptor binding assays within neurobiological research.
• Peptide Library Synthesis: Serves as a critical component in combinatorial chemistry for generating diverse peptide libraries for high-throughput screening.
• Neuropeptide Analog Development: Employed in the design and development of analogs for studying neurological pathways and potential therapeutic interventions.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental and applied life science research.

Basic Information

Product Name	Pyr-Phe-Gly-Nh2
CAS No.	203396-25-2
Molecular Formula	C19H22N4O4
Molecular Weight	370.41 g/mol
Synonyms	Pyroglutamyl-Phenylalanyl-Glycinamide; pGlu-Phe-Gly-NH2; 5-Oxo-L-prolyl-L-phenylalanylglycinamide; L-Pyroglutamyl-L-phenylalanylglycine amide; Pyr-Phe-Gly-amide; TRH-Related Peptide Fragment; pGlu-Phe-Gly-NH2
EINECS	Contact for details

Quality Control

Our Pyr-Phe-Gly-Nh2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral purity checks, to ensure it meets the stringent requirements of research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.