Description

4-Bromo-3,5-Difluoroaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the difluoro and bromo substituents enhance biological activity.
• Material Science: Building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing halogen groups.
• Dye and Pigment Manufacturing: Intermediate in the production of complex, high-performance dyes and pigments.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Research & Development: Essential reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4-Bromo-3,5-Difluoroaniline
CAS No.	203302-95-8
Molecular Formula	C6H4BrF2N
Molecular Weight	208.00 g/mol
Synonyms	3,5-Difluoro-4-bromoaniline; 4-Bromo-3,5-difluorobenzenamine; 1-Amino-4-bromo-3,5-difluorobenzene; Benzenamine, 4-bromo-3,5-difluoro-; Aniline, 4-bromo-3,5-difluoro-
EINECS	Contact for details

Quality Control

Our 4-Bromo-3,5-Difluoroaniline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.