Description

2-Bromo-5-Fluoro-4-Methylaniline is a halogenated aniline derivative serving as a versatile and high-value building block in advanced organic synthesis. Its core value proposition lies in its unique substitution pattern, which enables the precise introduction of bromine and fluorine atoms into complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine and bromine atoms can enhance efficacy and environmental profile.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors or liquid crystals, where its electronic properties are valuable.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing specialized halogenated dyes and pigments.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromine atom, enabling carbon-carbon and carbon-heteroatom bond formation.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-Bromo-5-Fluoro-4-Methylaniline
CAS No.	202865-78-9
Molecular Formula	C7H7BrFN
Molecular Weight	204.04 g/mol
Synonyms	4-Methyl-2-bromo-5-fluoroaniline; 2-Bromo-5-fluoro-p-toluidine; 5-Fluoro-2-bromo-4-methylaniline; 2-Bromo-5-fluoro-4-methylbenzenamine; Benzenamine, 2-bromo-5-fluoro-4-methyl-; 4-Amino-2-bromo-5-fluorotoluene; 2-Bromo-5-fluoro-4-methyl-phenylamine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluoro-4-Methylaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.