Description

4-Bromo-2-Fluorobenzaldoxime is a versatile halogenated aromatic oxime building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on the synthesis of novel active ingredients, functional materials, and specialized ligands.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine and bromine atoms contribute to biological activity and metabolic stability.
• Ligand Precursor: Serves as a precursor for the preparation of specialized bidentate or tridentate ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized aromatic polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes and tags for studying biological systems.

Basic Information

Product Name	4-Bromo-2-Fluorobenzaldoxime
CAS No.	202865-64-3
Molecular Formula	C7H5BrFNO
Molecular Weight	218.03 g/mol
Synonyms	2-Fluoro-4-bromobenzaldoxime; (2-Fluoro-4-bromophenyl)methanone oxime; Benzaldehyde, 4-bromo-2-fluoro-, oxime; 4-Bromo-2-fluorobenzaldehyde oxime; 202865-64-3; 4-Bromo-2-fluoro-benzaldoxime; 4-Bromo-2-fluorobenzaldehyde oxime (E/Z mixture)
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorobenzaldoxime is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.