Description

4'-Methoxy[1,1'-Biphenyl]-4-Sulfonyl Chloride is a high-purity, specialized sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile sulfonylation reagent, enabling the introduction of the biphenyl sulfonyl moiety into target molecules with high efficiency. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides that require specific biphenyl sulfonamide structures.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the creation of activity-based probes and affinity labels for studying enzyme function and protein interactions.
• Ligand Synthesis for Catalysis: A precursor for synthesizing specialized sulfonamide-based ligands used in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	4'-Methoxy[1,1'-Biphenyl]-4-Sulfonyl Chloride
CAS No.	202752-04-3
Molecular Formula	C13H11ClO3S
Molecular Weight	282.74 g/mol
Synonyms	4-(4-Methoxyphenyl)benzenesulfonyl chloride; [1,1'-Biphenyl]-4-sulfonyl chloride, 4'-methoxy-; 4'-Methoxybiphenyl-4-sulfonyl chloride; p-Methoxybiphenyl-4'-sulfonyl chloride; 4-Methoxy-4'-sulfonylchlorobiphenyl; (4'-Methoxy[1,1'-biphenyl]-4-yl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4'-Methoxy[1,1'-Biphenyl]-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0 - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.