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n-(S-Nitroso-n-Acetyl-D,L-Penicillamine)-2-Amino-2-Deoxy-1,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranose CAS NO 202656-49-3


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CAS No.:202656-49-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-(S-Nitroso-n-Acetyl-D,L-Penicillamine)-2-Amino-2-Deoxy-1,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranose is a sophisticated, high-purity chemical intermediate designed for advanced research and synthesis. This compound is valued for its unique structure, which combines a nitrosothiol donor moiety with a protected glucosamine derivative, making it a critical reagent in nitric oxide (NO) research and targeted drug delivery systems. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and specialty chemical manufacturers focused on developing novel therapeutics and biochemical probes.

Application

  • Nitric Oxide (NO) Donor Research: Serves as a key precursor or model compound for studying NO release kinetics and signaling pathways in biological systems.
  • Pharmaceutical Intermediate: Used in the synthesis of targeted prodrugs and conjugates designed for site-specific delivery of nitric oxide or other active agents.
  • Biochemical Probe Development: Acts as a building block for creating labeled compounds used to investigate enzyme activity, cell-surface interactions, and metabolic pathways.
  • Glycoconjugate Chemistry: The protected glucopyranose structure makes it valuable for synthesizing complex glycoconjugates and studying carbohydrate-protein interactions.
  • Cardiovascular & Neurological Research: Applied in preclinical studies exploring the role of NO in vasodilation, neurotransmission, and related therapeutic areas.

Basic Information

Product Name n-(S-Nitroso-n-Acetyl-D,L-Penicillamine)-2-Amino-2-Deoxy-1,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranose
CAS No. 202656-49-3
Molecular Formula C₂₁H₃₁N₃O₁₂S
Molecular Weight 549.55 g/mol
Synonyms SNAP-GlcNAc; N-Acetyl-S-nitrosopenicillamine Glucosamine Tetraacetate; 2-Amino-2-deoxy-1,3,4,6-tetra-O-acetyl-β-D-glucopyranose N-(S-Nitroso-N-acetyl-D,L-penicillamine) ester; NO-Donor Glucosamine Conjugate; S-Nitroso-N-acetylpenicillamine glucosamine tetraacetate; SNAP-conjugated tetraacetylglucosamine; Nitrosothiol glucosamine derivative
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Quality Control

This high-value intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere for long-term stability. This compound is light-sensitive and may be moisture-sensitive; allow the sealed container to equilibrate to room temperature before opening to prevent condensation. Keep away from strong oxidizers and bases.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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