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n-(S-Nitroso-n-Acetyl-D,L-Penicillamine)-2-Amino-2-Deoxy-1,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranose CAS NO 202656-49-3
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CAS No.:202656-49-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-(S-Nitroso-n-Acetyl-D,L-Penicillamine)-2-Amino-2-Deoxy-1,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranose is a sophisticated, high-purity chemical intermediate designed for advanced research and synthesis. This compound is valued for its unique structure, which combines a nitrosothiol donor moiety with a protected glucosamine derivative, making it a critical reagent in nitric oxide (NO) research and targeted drug delivery systems. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and specialty chemical manufacturers focused on developing novel therapeutics and biochemical probes.
Application
- Nitric Oxide (NO) Donor Research: Serves as a key precursor or model compound for studying NO release kinetics and signaling pathways in biological systems.
- Pharmaceutical Intermediate: Used in the synthesis of targeted prodrugs and conjugates designed for site-specific delivery of nitric oxide or other active agents.
- Biochemical Probe Development: Acts as a building block for creating labeled compounds used to investigate enzyme activity, cell-surface interactions, and metabolic pathways.
- Glycoconjugate Chemistry: The protected glucopyranose structure makes it valuable for synthesizing complex glycoconjugates and studying carbohydrate-protein interactions.
- Cardiovascular & Neurological Research: Applied in preclinical studies exploring the role of NO in vasodilation, neurotransmission, and related therapeutic areas.
Basic Information
| Product Name | n-(S-Nitroso-n-Acetyl-D,L-Penicillamine)-2-Amino-2-Deoxy-1,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranose |
| CAS No. | 202656-49-3 |
| Molecular Formula | C₂₁H₃₁N₃O₁₂S |
| Molecular Weight | 549.55 g/mol |
| Synonyms | SNAP-GlcNAc; N-Acetyl-S-nitrosopenicillamine Glucosamine Tetraacetate; 2-Amino-2-deoxy-1,3,4,6-tetra-O-acetyl-β-D-glucopyranose N-(S-Nitroso-N-acetyl-D,L-penicillamine) ester; NO-Donor Glucosamine Conjugate; S-Nitroso-N-acetylpenicillamine glucosamine tetraacetate; SNAP-conjugated tetraacetylglucosamine; Nitrosothiol glucosamine derivative |
| EINECS | Contact for details |
Quality Control
This high-value intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere for long-term stability. This compound is light-sensitive and may be moisture-sensitive; allow the sealed container to equilibrate to room temperature before opening to prevent condensation. Keep away from strong oxidizers and bases.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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