Description

4-Fluoro-2-(Trifluoromethyl)Benzylamine is a high-purity fluorinated aromatic amine building block of significant interest in advanced chemical synthesis. Its molecular structure, featuring both fluorine and a trifluoromethyl group, makes it a valuable precursor for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas like kinase inhibitors and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine motifs enhance biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter surface properties, chemical resistance, and durability.
• Cross-coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) to create complex aromatic amines.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	4-Fluoro-2-(Trifluoromethyl)Benzylamine
CAS No.	202522-22-3
Molecular Formula	C8H7F4N
Molecular Weight	193.14 g/mol
Synonyms	α-(Aminomethyl)-5-fluoro-α,α,α-trifluoro-o-toluidine; (4-Fluoro-2-(trifluoromethyl)phenyl)methanamine; 2-(Trifluoromethyl)-4-fluorobenzylamine; 4-Fluoro-α,α,α-trifluoro-o-toluidine; 5-Fluoro-2-(trifluoromethyl)benzylamine; 4-Fluoro-2-trifluoromethylbenzylamine; 4-Fluoro-α,α,α-trifluoro-o-toluamine
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(Trifluoromethyl)Benzylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.