Description

(D-Leu6,Pro-Nhet9)-Lhrh (4-9) is a synthetic peptide fragment derived from the Luteinizing Hormone-Releasing Hormone (LHRH) sequence, designed for enhanced stability and specific biological activity. This compound is critical for advanced research in endocrinology and neurobiology, serving as a valuable tool for studying receptor interactions and signal transduction pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on peptide-based therapeutic discovery and diagnostic development.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of gonadotropin secretion and reproductive endocrinology.
• Pharmacological Studies: Investigation of LHRH receptor binding affinity, agonist/antagonist activity, and structure-activity relationships (SAR).
• Drug Discovery: A key intermediate or lead compound in the development of novel peptide therapeutics for hormone-related disorders.
• Diagnostic Development: Potential use in the development of immunoassays and other diagnostic tools for hormonal function.
• Neuroscience Research: Exploration of the neuromodulatory functions of LHRH fragments in the central nervous system.

Basic Information

Product Name	(D-Leu6,Pro-Nhet9)-Lhrh (4-9)
CAS No.	202333-85-5
Molecular Formula	C38H58N12O8
Molecular Weight	810.95 g/mol
Synonyms	LHRH (4-9) fragment, D-Leu6,Pro-NHEt9-LHRH (4-9); Luteinizing Hormone-Releasing Hormone (4-9) analog; Pyro-Glu-His-Trp-Ser-Tyr-D-Leu-Pro-NHEt; Gonadotropin-Releasing Hormone (GnRH) fragment (4-9); [D-Leu6, Pro9-NHEt]-LHRH (4-9); pGlu-His-Trp-Ser-Tyr-D-Leu-Pro-NHEt; LHRH agonist fragment
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of (D-Leu6,Pro-Nhet9)-Lhrh (4-9) undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, content, and chromatographic data are provided to ensure compliance with research-grade standards and support your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.