Description

L-Aspartic Acid-n-T-Boc, B-Bz Ester (13C4,15N) is a high-purity, isotopically labeled derivative of aspartic acid, specifically designed for advanced research and development. This compound is a critical building block for the synthesis of peptides and proteins with stable isotope labels, enabling precise metabolic tracing and structural analysis. It is essential for scientists in pharmaceutical R&D, proteomics, and metabolic studies who require the highest standards of isotopic purity and chemical stability for their analytical and synthetic workflows.

Application

• Stable Isotope Labeling in Proteomics: Used as a labeled precursor in the synthesis of isotopically coded peptides for mass spectrometry-based quantitative proteomics (e.g., SILAC, AQUA).
• Metabolic Pathway Tracing: Serves as a 13C and 15N-labeled tracer to study amino acid metabolism, protein turnover, and biosynthetic pathways in biological systems.
• Pharmaceutical Research: A key intermediate in the development of novel peptide-based therapeutics and diagnostic agents, where isotopic labels are used for pharmacokinetic and biodistribution studies.
• NMR Spectroscopy: Provides a site-specific isotopic label for nuclear magnetic resonance (NMR) studies to determine protein structure, dynamics, and interactions.
• Biochemical Research Reagent: Employed in enzymatic studies and as a standard for analytical method development in chromatography and mass spectrometry.

Basic Information

Product Name	L-Aspartic Acid-n-T-Boc, B-Bz Ester (13C4,15N)
CAS No.	202326-58-7
Molecular Formula	C16H2013C415N O6
Molecular Weight	Contact for details
Synonyms	N-α-(tert-Butoxycarbonyl)-O4-benzyl-L-aspartic acid-13C4,15N; Boc-Asp(OBzl)-OH-13C4,15N; (2S)-2-[(tert-Butoxycarbonyl)amino]-4-(benzyloxy)-4-oxobutanoic acid-1,2,3,4-13C4,15N; Boc-L-Asp(OBzl)-OH-13C4,15N; L-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 4-(phenylmethyl) ester-13C4,15N; Boc-Aspartic acid β-benzyl ester-13C4,15N; Isotopically labeled Boc-Asp(OBzl)-OH
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with the stringent requirements for isotopically labeled compounds. Each batch is characterized to confirm isotopic enrichment (Atom % 13C and 15N), chemical purity, and chiral integrity. Certificates of Analysis (COA) are provided, detailing results from NMR, HPLC, and mass spectrometry analyses. We adhere to quality management principles suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom % 13C
Isotopic Enrichment (15N)	≥ 98 atom % 15N
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.