Description

D-Glucosamine-2-N,6-o-Disulphatedisodiumsalt is a highly specific, sulfated derivative of the amino sugar glucosamine, distinguished by its dual sulfate groups at the N-2 and O-6 positions. This precise chemical modification is critical for advanced biochemical research and development, particularly in the study of glycosaminoglycan (GAG) analogs and carbohydrate-protein interactions. It serves as a valuable reference standard and building block for pharmaceutical and biotechnology companies focused on developing novel therapeutics for conditions related to joint health, inflammation, and extracellular matrix biology.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity assessment, and quantification of related compounds in drug development and quality control laboratories.
• Biochemical Research Reagent: Essential for studying enzyme kinetics (e.g., sulfatases, glycosyltransferases) and investigating the structure-activity relationships of sulfated carbohydrates.
• Glycosaminoglycan (GAG) Mimetic Synthesis: Acts as a key intermediate or precursor in the synthesis of heparin/heparan sulfate analogs for anticoagulant and anti-inflammatory research.
• Cell Biology & Signal Transduction Studies: Employed to probe the role of specific sulfation patterns in cell signaling, growth factor binding, and receptor activation pathways.
• Diagnostic Kit Development: Utilized in the formulation of calibration standards and controls for diagnostic assays targeting carbohydrate biomarkers.
• Academic & Institutional Research: Supports fundamental research in glycobiology, chemical biology, and medicinal chemistry at universities and research institutes.

Basic Information

Product Name	D-Glucosamine-2-N,6-o-Disulphatedisodiumsalt
CAS No.	202266-99-7
Molecular Formula	C6H11NNa2O11S2
Molecular Weight	391.27 g/mol
Synonyms	Disodium D-Glucosamine-2-N,6-O-disulfate; Glucosamine 2,6-Disulfate Disodium Salt; 2-N,6-O-Disulfoglucosamine Disodium Salt; D-Glucosamine-2,6-bis(hydrogen sulfate) disodium salt; 2-Deoxy-2-sulfoamino-D-glucopyranose 6-(hydrogen sulfate) disodium salt; (2R,3R,4R,5S)-3,4,5-Trihydroxy-6-(sulfooxy)-2-(sulfoamino)hexyl sodium sulfate; GlcN-2,6-S Disodium Salt
EINECS	Contact for details

Quality Control

Our D-Glucosamine-2-N,6-o-Disulphatedisodiumsalt is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
pH (5% solution)	5.0 - 7.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.