Description

2-[4-(Bromomethyl)Phenyl]-1,1,1,3,3,3-Hexafluoropropan-2-Ol is a high-value fluorinated aromatic building block characterized by its reactive bromomethyl and hexafluoroisopropanol functional groups. This compound is essential for advanced organic synthesis, enabling the precise introduction of fluorinated motifs and facilitating further derivatization. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides with enhanced biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated monomers used in electronic display and lighting technologies.
• Polymer Modification: Incorporates fluorinated segments into polymers to impart unique properties like oil/water repellency and chemical resistance.
• Cross-Coupling Reactions: The bromomethyl group acts as a versatile handle for Suzuki, Sonogashira, and other palladium-catalyzed coupling reactions.
• Ligand & Catalyst Design: Building block for synthesizing sophisticated fluorinated ligands used in asymmetric catalysis.

Basic Information

Product Name	2-[4-(Bromomethyl)Phenyl]-1,1,1,3,3,3-Hexafluoropropan-2-Ol
CAS No.	202134-57-4
Molecular Formula	C10H7BrF6O
Molecular Weight	337.06 g/mol
Synonyms	4-(Bromomethyl)-α,α-bis(trifluoromethyl)benzenemethanol; 1-[4-(Bromomethyl)phenyl]-2,2,2-trifluoro-1-(trifluoromethyl)ethanol; 2-(4-Bromomethylphenyl)hexafluoroisopropanol; Hexafluoro-2-(4-(bromomethyl)phenyl)propan-2-ol; p-Bromomethyl-α,α-bis(trifluoromethyl)benzyl Alcohol; (4-Bromomethylphenyl)hexafluoroisopropanol
EINECS	Contact for details

Quality Control

Our 2-[4-(Bromomethyl)Phenyl]-1,1,1,3,3,3-Hexafluoropropan-2-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.