Description

Meosuc-Gly-Leu-Phe-Amc CAS NO 201854-05-9 is a specialized fluorogenic peptide substrate designed for high-sensitivity enzymatic assays. This compound is critical for researchers and quality control laboratories requiring precise measurement of protease activity, particularly for enzymes like human neutrophil elastase. It is primarily utilized in pharmaceutical R&D, biochemical research, and diagnostic kit development, where reliable and reproducible substrate performance is non-negotiable.

Application

• Protease Activity Assays: A key fluorogenic substrate for kinetic studies and inhibitor screening of serine proteases, including human leukocyte elastase (HLE).
• Pharmaceutical Research: Used in high-throughput screening (HTS) platforms to identify and characterize novel elastase inhibitors for therapeutic development.
• Biochemical Research: Essential for studying enzyme kinetics, mechanism of action, and substrate specificity in academic and industrial laboratories.
• Diagnostic Development: Employed in the formulation of diagnostic kits for detecting and quantifying protease levels in clinical and research samples.
• Quality Control: Serves as a reference standard in QC laboratories for batch consistency testing of related enzymatic products and assays.

Basic Information

Product Name	Meosuc-Gly-Leu-Phe-Amc
CAS No.	201854-05-9
Molecular Formula	C27H38N4O8
Molecular Weight	546.62 g/mol
Synonyms	N-Methoxysuccinyl-Gly-Leu-Phe-7-amido-4-methylcoumarin; MeOSuc-Gly-Leu-Phe-AMC; Methoxysuccinyl-Gly-Leu-Phe-AMC; Elastase Substrate IV; HLE Substrate; Human Leukocyte Elastase Substrate; 7-Amido-4-methylcoumarin derivative; Fluorogenic elastase substrate.
EINECS	Contact for details

Quality Control

Every batch of Meosuc-Gly-Leu-Phe-Amc is manufactured and tested under strict quality management systems. We guarantee high purity and batch-to-batch consistency, supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation, and other critical parameters is provided with each shipment to ensure compliance with your research and development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (Mass Spec)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.