Description

H-Asp(Pna)-Oh Hcl is a protected aspartic acid derivative, specifically the hydrochloride salt of aspartic acid β-benzyl ester. This compound serves as a crucial building block and intermediate in sophisticated organic synthesis, particularly for peptide chemistry. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity, specialized amino acid derivatives for drug discovery and development.

Application

• Peptide Synthesis: A key protected intermediate for the solid-phase and solution-phase synthesis of peptides and peptidomimetics.
• Pharmaceutical Research: Used in the research and development of new active pharmaceutical ingredients (APIs), especially those involving aspartic acid motifs.
• Bioconjugation: Acts as a linker or spacer molecule in the design of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology: Employed in the study of enzyme mechanisms and protein-protein interactions where modified amino acids are required.
• Material Science: Potential use in the synthesis of specialized polymers and biomaterials with tailored properties.

Basic Information

Product Name	H-Asp(Pna)-Oh Hcl
CAS No.	201732-79-8
Molecular Formula	C11H14ClNO4
Molecular Weight	259.69 g/mol
Synonyms	L-Aspartic acid β-benzyl ester hydrochloride; Aspartic acid 4-benzyl ester hydrochloride; H-Asp(OBzl)-OH·HCl; (S)-2-Amino-3-(benzyloxycarbonyl)propanoic acid hydrochloride; (S)-2-Amino-3-(benzyloxy)-3-oxopropanoic acid hydrochloride; Aspartic acid benzyl ester HCl; β-Benzyl L-aspartate hydrochloride
EINECS	Contact for details

Quality Control

Our H-Asp(Pna)-Oh Hcl is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and our quality management system is designed to meet the stringent requirements of our global clientele in advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]²⁰D: Specific range available on COA
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.