Description

n-Acetyl-S-(2-Carboxyethyl)-L-Cysteine Bis(Dicyclohexylamine) Salt is a high-purity, chemically defined derivative of L-cysteine, primarily used as a critical reference standard and synthetic intermediate. This compound is essential for analytical method development and validation in bioanalytical and pharmacokinetic studies, particularly for tracking mercapturic acid pathway metabolites. It is a vital material for pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of diagnostic reagents requiring precise and reliable analytical standards.

Application

• Reference Standard for Bioanalysis: Primary use as a certified reference material (CRM) for the quantification of mercapturic acid conjugates in biological matrices via LC-MS/MS or HPLC.
• Metabolite Research: Studying the metabolism and detoxification pathways of electrophilic compounds, acrylates, and other xenobiotics in toxicology and pharmacology.
• Biomarker Development: Serving as a synthetically accessible biomarker for human biomonitoring studies to assess exposure to industrial chemicals.
• Pharmaceutical Intermediate: Used in the synthesis of more complex cysteine derivatives or prodrugs targeting specific biological pathways.
• Quality Control in CROs: Essential for calibrating instruments and validating analytical methods in contract research and quality control laboratories.
• Academic Research: A key reagent in university and institutional research focused on glutathione metabolism, oxidative stress, and chemical toxicology.

Basic Information

Product Name	n-Acetyl-S-(2-Carboxyethyl)-L-Cysteine Bis(Dicyclohexylamine) Salt
CAS No.	201666-27-5
Molecular Formula	C11H17NO5S • 2(C12H23N)
Molecular Weight	Contact for details
Synonyms	N-Acetyl-S-(2-carboxyethyl)cysteine dicyclohexylamine salt; N-Acetyl-S-(2-carboxyethyl)-L-cysteine bis(dicyclohexylammonium) salt; Acetyl-S-(2-carboxyethyl)cysteine DCHA salt; Mercapturic acid derivative DCHA salt; N-Acetyl-3-[(2-carboxyethyl)thio]alanine dicyclohexylamine salt; ACE-Cys DCHA salt; AAMA DCHA salt (Acrylamide metabolite derivative)
EINECS	Contact for details

Quality Control

Our n-Acetyl-S-(2-Carboxyethyl)-L-Cysteine Bis(Dicyclohexylamine) Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the high standards required for reference materials. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	95.0% - 105.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.