Description

2-Chloro-3,5-Bis(Trifluoromethyl)Aniline is a high-value, halogenated aniline derivative characterized by its trifluoromethyl substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in the synthesis of complex organic molecules. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the trifluoromethyl groups.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of fluorinated polymers and advanced organic electronic materials for enhanced stability and performance.
• Custom Synthesis and Contract Manufacturing: A crucial starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	2-Chloro-3,5-Bis(Trifluoromethyl)Aniline
CAS No.	201593-90-0
Molecular Formula	C9H4ClF6N
Molecular Weight	275.58 g/mol
Synonyms	2-Chloro-3,5-bis(trifluoromethyl)benzenamine; 2-Chloro-alpha,alpha,alpha,alpha',alpha',alpha'-hexafluoro-m-xylidine; 3,5-Bis(trifluoromethyl)-2-chloroaniline; Benzenamine, 2-chloro-3,5-bis(trifluoromethyl)-; 2-Chloro-3,5-di(trifluoromethyl)aniline
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-3,5-Bis(Trifluoromethyl)Aniline adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support development and commercial projects requiring material produced under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.