Description

L-Alanine-n-Fmoc (3-13C) is a carbon-13 labeled derivative of N-Fmoc-L-alanine, a fundamental building block in solid-phase peptide synthesis (SPPS). This isotopically enriched compound is essential for advanced research applications requiring precise molecular tracking and analysis. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies specializing in peptide-based drug discovery, metabolic studies, and nuclear magnetic resonance (NMR) spectroscopy.

Application

• Peptide Synthesis Research: As a 13C-labeled amino acid derivative for the controlled synthesis of isotopically labeled peptides.
• Metabolic Pathway Tracing: Employed in biochemical research to track the incorporation and fate of alanine in metabolic studies.
• NMR Spectroscopy: Serves as a crucial reagent for preparing isotopically labeled peptides and proteins for structural and dynamic analysis via NMR.
• Proteomics & Biomarker Discovery: Used in quantitative proteomics and mass spectrometry-based studies for internal standardization and accurate quantification.
• Pharmaceutical Development: Integral in the research and development stages of novel peptide therapeutics and diagnostic agents.
• Academic Research: A key material for investigating peptide chemistry, enzyme mechanisms, and protein-protein interactions in a laboratory setting.

Basic Information

Product Name	L-Alanine-n-Fmoc (3-13C)
CAS No.	201489-21-6
Molecular Formula	C18H1713CNO4
Molecular Weight	Contact for details
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine-3-13C; Fmoc-L-Ala-3-13C; Fmoc-L-alanine-3-13C; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]propanoic-3-13C acid; N-Fmoc-L-alanine-3-13C; Fmoc-Ala-3-13C-OH; Fmoc-13C-L-Ala-OH; Fmoc-L-Alanine (3-13C)
EINECS	Contact for details

Quality Control

Our L-Alanine-n-Fmoc (3-13C) is manufactured under strict quality control protocols to ensure high isotopic and chemical purity suitable for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment, chemical purity (by HPLC), and chiral purity. We adhere to cGMP guidelines for the production of research-grade biochemicals, ensuring reliable consistency and traceability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom %
Optical Rotation	Specific range provided on COA
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.