Description

Ethyl 6-Methyl-2-Oxo-4-(3,4,5-Trimethoxyphenyl)-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is a high-purity, synthetically valuable tetrahydropyrimidine derivative, also known as a Biginelli reaction product. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis for research and development. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry research.
• Chemical Synthesis Scaffold: Serves as a core structure for the development of libraries of novel heterocyclic compounds via further derivatization.
• Research & Development: Used in academic and industrial R&D settings to study structure-activity relationships (SAR) and biological activity.
• Biginelli Reaction Studies: Acts as a reference compound or product in methodological studies and catalysis research related to the multicomponent Biginelli reaction.

Basic Information

Product Name	Ethyl 6-Methyl-2-Oxo-4-(3,4,5-Trimethoxyphenyl)-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
CAS No.	201287-92-5
Molecular Formula	C₁₉H₂₄N₂O₆
Molecular Weight	376.41 g/mol
Synonyms	Ethyl 4-(3,4,5-Trimethoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 5-Carbethoxy-6-methyl-4-(3,4,5-trimethoxyphenyl)-3,4-dihydropyrimidin-2(1H)-one; Biginelli Product Derivative; DHPM Derivative; 1,2,3,4-Tetrahydropyrimidine-5-carboxylic acid, 6-methyl-2-oxo-4-(3,4,5-trimethoxyphenyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Methyl-2-Oxo-4-(3,4,5-Trimethoxyphenyl)-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.