Description

Boc-Ser(p-Chloro-Bzl)-Oh Dcha is a protected amino acid derivative, specifically the tert-butyloxycarbonyl (Boc) derivative of O-(p-chlorobenzyl)-L-serine as a dicyclohexylamine (DCHA) salt. This compound is a critical building block in solid-phase peptide synthesis (SPPS), where it provides a protected serine residue with orthogonal side-chain protection. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers engaged in the development of therapeutic peptides, peptidomimetics, and complex organic molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid precursor for the controlled incorporation of serine into peptide chains.
• Pharmaceutical Intermediates: Serves as a crucial intermediate in the research and production of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation & Labeling: Used in the synthesis of peptide conjugates for drug delivery systems, diagnostics, and biophysical studies.
• Chemical Biology Research: Employed in the synthesis of custom peptides for probing protein-protein interactions, enzyme activity, and cellular processes.
• Process Development: Used in scaling up synthetic routes for novel peptide therapeutics in both academic and industrial R&D settings.

Basic Information

Product Name	Boc-Ser(p-Chloro-Bzl)-Oh Dcha
CAS No.	201208-64-2
Molecular Formula	C21H32ClNO5 • C12H23N
Molecular Weight	~585.1 g/mol (as free acid, C21H32ClNO5)
Synonyms	N-α-(tert-Butoxycarbonyl)-O-(4-chlorobenzyl)-L-serine dicyclohexylamine salt; Boc-Ser(Bzl(4-Cl))-OH • DCHA; Boc-O-(p-Chlorobenzyl)-L-serine DCHA salt; tert-Butyloxycarbonyl-O-(4-chlorobenzyl)serine dicyclohexylammonium salt; (S)-2-((tert-Butoxycarbonyl)amino)-3-((4-chlorobenzyl)oxy)propanoic acid dicyclohexylamine salt; Boc-Ser(4-Cl-Bzl)-OH DCHA; Boc-L-Ser(p-Cl-Bzl)-OH DCHA salt
EINECS	Contact for details

Quality Control

Our Boc-Ser(p-Chloro-Bzl)-Oh Dcha is manufactured under strict quality control protocols to ensure high chemical purity and batch-to-batch consistency, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.