Description

Fmoc-Lys(Me3)-Oh Hcl is a protected amino acid derivative, specifically an Fmoc-protected, side-chain methylated lysine building block. This compound is essential for the solid-phase synthesis of peptides, where it provides precise control over the incorporation of modified lysine residues. It is a critical raw material for researchers and manufacturers in pharmaceutical development, peptide therapeutics, and biochemical research who require high-purity, specialty amino acids.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled introduction of trimethylated lysine analogs into peptide chains.
• Pharmaceutical Research: Synthesis of peptide-based drug candidates, particularly those targeting epigenetic regulation where histone mimicry is involved.
• Bioconjugation & Protein Engineering: Used to create chemically modified peptides for studying protein-protein interactions and function.
• Academic & Industrial R&D: Fundamental research in chemical biology, epigenetics, and the development of novel therapeutic peptides.
• Production of Custom Peptides: Serves as a specialty monomer for CROs and CDMOs producing bespoke peptides for clients.

Basic Information

Product Name	Fmoc-Lys(Me3)-Oh Hcl
CAS No.	201004-29-7
Molecular Formula	C26H34N2O5 • HCl
Molecular Weight	491.02 g/mol (for free base C26H34N2O5)
Synonyms	Fmoc-Lys(Me3)-OH•HCl; Nε-Trimethyl-Fmoc-L-lysine hydrochloride; Fmoc-Nε-trimethyl-L-lysine hydrochloride; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(trimethylammonio)hexanoate chloride; Fmoc-Lys(Me3)-OH hydrochloride; Nα-Fmoc-Nε-trimethyl-L-lysine hydrochloride; Fmoc-Nε-Me3-L-Lys-OH•HCl
EINECS	Contact for details

Quality Control

Our Fmoc-Lys(Me3)-Oh Hcl is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and cGMP manufacturing. Each lot undergoes rigorous analytical testing including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing assay, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.