Description

2-[2-(Methylsulfanyl)-4-Pyrimidinyl]-1-[3-(Trifluoromethyl)Phenyl]-1-Ethanone is a high-value, specialized organic intermediate featuring a pyrimidine core functionalized with a methylthio group and a trifluoromethylphenyl ketone moiety. This compound is critical for its role as a key building block in modern pharmaceutical and agrochemical research, enabling the synthesis of complex molecules with targeted biological activity. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing advanced active ingredients for crop protection products, leveraging the bioactivity of the pyrimidine scaffold.
• Chemical Biology & Proteomics: Serves as a versatile probe or linker molecule in the study of protein-ligand interactions and biochemical pathways.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with unique electronic or surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development of scalable synthetic routes.

Basic Information

Product Name	2-[2-(Methylsulfanyl)-4-Pyrimidinyl]-1-[3-(Trifluoromethyl)Phenyl]-1-Ethanone
CAS No.	200801-88-3
Molecular Formula	C14H11F3N2OS
Molecular Weight	312.31 g/mol
Synonyms	1-[3-(Trifluoromethyl)phenyl]-2-[2-(methylthio)-4-pyrimidinyl]ethanone; 2-(2-Methylsulfanyl-pyrimidin-4-yl)-1-[3-(trifluoromethyl)phenyl]ethanone; 2-(2-(Methylthio)pyrimidin-4-yl)-1-(3-(trifluoromethyl)phenyl)ethanone; CAS 200801-88-3; Ethanone, 1-[3-(trifluoromethyl)phenyl]-2-[2-(methylthio)-4-pyrimidinyl]-; 2-(2-Methylmercapto-4-pyrimidinyl)-1-(3-trifluoromethylphenyl)ethanone
EINECS	Contact for details

Quality Control

Our 2-[2-(Methylsulfanyl)-4-Pyrimidinyl]-1-[3-(Trifluoromethyl)Phenyl]-1-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and cGMP-grade requirements for advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.