Description

6-(Trifluoromethyl)-5-Methylindoline CAS NO 200711-22-4 is a high-purity, advanced pharmaceutical intermediate featuring a unique indoline scaffold substituted with a trifluoromethyl group. This compound is valued for its role in modulating the pharmacokinetic and metabolic properties of target molecules, making it a critical building block in modern drug discovery. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Academic & R&D: Employed in university and corporate laboratories for methodological studies and the exploration of new chemical reactions involving fluorinated heterocycles.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	6-(Trifluoromethyl)-5-Methylindoline
CAS No.	200711-22-4
Molecular Formula	C10H10F3N
Molecular Weight	201.19 g/mol
Synonyms	5-Methyl-6-(trifluoromethyl)indoline; 5-Methyl-6-(trifluoromethyl)-2,3-dihydro-1H-indole; 1H-Indole, 2,3-dihydro-5-methyl-6-(trifluoromethyl)-; 6-Trifluoromethyl-5-methylindoline; Indoline, 6-(trifluoromethyl)-5-methyl-
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)-5-Methylindoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.