Description

6-(Trifluoromethyl)Indolin-5-Ol is a high-value fluorinated indoline derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both an indoline scaffold and a trifluoromethyl group, makes it indispensable for constructing complex molecules with enhanced biological activity and metabolic stability. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the trifluoromethyl group can improve lipophilicity and environmental persistence.
• Material Science Precursor: Employed in the creation of specialty polymers and organic electronic materials that require fluorinated aromatic components.
• Ligand Synthesis: Serves as a precursor for complex ligands used in catalysis and asymmetric synthesis.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	6-(Trifluoromethyl)Indolin-5-Ol
CAS No.	200711-19-9
Molecular Formula	C9H8F3NO
Molecular Weight	203.16 g/mol
Synonyms	5-Hydroxy-6-(trifluoromethyl)indoline; 6-(Trifluoromethyl)-5-hydroxyindoline; 5-Indolinol, 6-(trifluoromethyl)-; 200711-19-9; 6-Trifluoromethylindolin-5-ol; 5-Hydroxy-6-trifluoromethylindoline; 6-(Trifluoromethyl)-1,3-dihydro-2H-indol-5-ol
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)Indolin-5-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.