Description

Leptin (93-105) (Human) is a synthetic peptide fragment corresponding to amino acids 93-105 of the human leptin hormone. This high-purity peptide is a critical research tool for studying the structure-activity relationships, receptor binding mechanisms, and signaling pathways of leptin. It is essential for researchers and developers in the pharmaceutical and biotechnology sectors focused on metabolic disorders, obesity research, and therapeutic peptide development.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating leptin's role in appetite regulation, energy homeostasis, and fat metabolism.
• Receptor Binding Assays: Employed in competitive binding studies and ELISA tests to characterize interactions with the leptin receptor (Ob-R).
• Structure-Activity Relationship (SAR) Studies: Serves as a key fragment for mapping the bioactive regions of the full-length leptin protein to identify minimal functional sequences.
• Antibody Production & Immunoassays: Acts as an antigen for generating specific polyclonal or monoclonal antibodies against defined epitopes of human leptin.
• Pharmaceutical Development: Utilized in early-stage discovery and preclinical testing for novel therapeutics targeting metabolic syndromes.
• Cell Signaling & In Vitro Studies: Applied in cell culture models to stimulate or inhibit leptin-specific pathways and assess downstream effects.

Basic Information

Product Name	Leptin (93-105) (Human)
CAS No.	200436-43-7
Molecular Formula	C66H105N19O21S
Molecular Weight	1500.73 g/mol
Synonyms	Human Leptin Fragment 93-105; Leptin (93-105); Leptin 93-105; H-Leu-Asp-Leu-His-Val-Leu-Asp-Lys-Val-Glu-Val-Ala-Cys-OH; LEP (93-105); Obese Protein (93-105); Peptide LEP 93-105
EINECS	Contact for details

Quality Control

Our Leptin (93-105) (Human) is manufactured under strict quality systems. Each batch is characterized using advanced analytical techniques including HPLC and mass spectrometry to ensure high purity and correct sequence verification. Certificates of Analysis (COA) providing detailed results for identity, purity, and peptide content are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	Within ± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.