Description

D-Aspartic Acid α-Amide Hydrochloride is a high-purity, chemically defined derivative of D-aspartic acid, a non-proteinogenic amino acid. This compound is valued for its role as a critical chiral building block and intermediate in advanced organic synthesis, particularly in the pharmaceutical and biotechnology sectors. It is essential for researchers and manufacturers developing peptide-based therapeutics, enzyme inhibitors, and other bioactive molecules where stereochemical purity is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel peptide drugs, hormone analogs, and enzyme inhibitors.
• Biochemical Research: Used in studies of enzyme kinetics, receptor-ligand interactions, and metabolic pathways involving D-amino acids.
• Peptide Synthesis: Serves as a protected D-aspartic acid derivative in solid-phase and solution-phase peptide synthesis to control regiochemistry.
• Asymmetric Catalysis: Employed as a precursor for chiral ligands or catalysts in asymmetric synthesis.
• Reference Standard: Utilized as an analytical standard in HPLC and LC-MS for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	D-Aspartic Acid α-Amide Hydrochloride
CAS No.	200260-37-3
Molecular Formula	C4H9N2O3·HCl
Molecular Weight	184.59 g/mol
Synonyms	D-Aspartic acid α-amide hydrochloride; (R)-2-Aminosuccinamic acid hydrochloride; D-Asparagine, N-amide hydrochloride (ambiguous); D-AAH HCl; D-2-Aminosuccinamic acid hydrochloride; (R)-Aminosuccinamic acid hydrochloride; D-Aspartic acid amide hydrochloride; H-D-Asp-NH2·HCl
EINECS	Contact for details

Quality Control

Our D-Aspartic Acid α-Amide Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% D-isomer
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.