Description

Fmoc-D-Asn(Mtt)-Oh is a protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound is specifically engineered to provide orthogonal protection for the side chain of D-asparagine, enabling the synthesis of complex and sensitive peptide sequences. It is a critical building block for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing peptide-based therapeutics and diagnostic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key monomer for the controlled, sequential assembly of peptides using Fmoc-chemistry protocols.
• Pharmaceutical Research: Used in the discovery and development of novel peptide drugs, hormones, and vaccines.
• Bioconjugation: Serves as a precursor for creating peptide-protein or peptide-small molecule conjugates.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening of bioactive peptide leads.
• Process Development: Used in scaling up GMP-grade peptide APIs for clinical and commercial manufacturing.
• Academic Research: A fundamental reagent for studying peptide structure, function, and synthesis methodologies.

Basic Information

Item	Detail
Product Name	Fmoc-D-Asn(Mtt)-Oh
CAS No.	200259-50-3
Molecular Formula	C41H36N2O6
Molecular Weight	652.74 g/mol
Synonyms	Fmoc-D-asparagine(Mtt)-OH; N-α-Fmoc-N-β-(4-methyltrityl)-D-asparagine; Fmoc-D-Asn(Mtt)-OH; N-(9-Fluorenylmethoxycarbonyl)-N'-(4-methyltrityl)-D-asparagine; Fmoc-D-Asparagine(Mtt)-OH; Fmoc-D-Asn(4-Mtt)-OH; (2R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[(4-methylphenyl)diphenylmethylamino]-3-oxopropanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-D-Asn(Mtt)-Oh is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for advanced peptide synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.