Description

Ac-Gly-Leu-Oh is a protected tripeptide derivative, specifically N-Acetyl-Glycyl-Leucine, with the CAS registry number 29852-55-9. This compound serves as a crucial building block and intermediate in advanced organic synthesis, particularly for peptide research and pharmaceutical development. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, well-characterized peptide fragments.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of novel therapeutic peptides and peptidomimetics.
• Biochemical Research: Serves as a standard or substrate in enzymatic studies and metabolic pathway investigations.
• Peptide Library Construction: A key component in solid-phase and solution-phase peptide synthesis for creating diverse compound libraries.
• Proteomics & Diagnostics: Can be utilized in the development of diagnostic assays and proteomic analysis tools.
• Cosmetic Peptides: Potential intermediate for the synthesis of bioactive peptides used in skincare formulations.
• Academic & Industrial R&D: Fundamental raw material for chemical biology and medicinal chemistry research programs.

Basic Information

Product Name	Ac-Gly-Leu-Oh
CAS No.	29852-55-9
Molecular Formula	C12H21N3O4
Molecular Weight	271.31 g/mol
Synonyms	N-Acetylglycylleucine; N-Acetyl-Gly-Leu-OH; Acetyl-Gly-Leu; Ac-Gly-Leu; N-Acetyl-Glycyl-L-leucine; L-Leucine, N-acetylglycyl-; N-Acetylglycyl-L-leucine; (2S)-2-[[2-(Acetylamino)acetyl]amino]-4-methylpentanoic acid
EINECS	Contact for details

Quality Control

Our Ac-Gly-Leu-Oh is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and spectroscopic identification (NMR, IR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with rigorous research and cGMP-grade standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.