Description

Glycyl-Sarcosine is a high-purity dipeptide derivative of glycine and sarcosine, widely recognized for its role as a model substrate in biochemical and pharmaceutical research. Its primary value lies in its utility for studying peptide transport systems, enzyme kinetics, and membrane permeability, providing critical insights for drug development. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors who require reliable, high-quality biochemical tools. The product is supplied under stringent quality controls to ensure batch-to-batch consistency for sensitive experimental applications.

Application

• Biochemical research as a standard substrate for studying the human peptide transporter 1 (hPepT1) and other membrane transporters.
• Pharmaceutical development for investigating drug absorption, bioavailability, and intestinal permeability of peptide-like drugs.
• Enzymology studies, serving as a specific substrate for enzymes like dipeptidyl peptidase IV (DPP-IV) and other proteases.
• Production of reference standards and calibrants for analytical methods such as HPLC and mass spectrometry.
• Nutritional and metabolic research to explore dipeptide absorption and utilization pathways.
• Cell culture and in vitro assay systems to model biological transport mechanisms.

Basic Information

Product Name	Glycyl-Sarcosine
CAS No.	29816-01-1
Molecular Formula	C5H10N2O3
Molecular Weight	146.15 g/mol
Synonyms	Gly-Sar; N-Glycylsarcosine; Glycine, N-(N-methylglycyl)-; L-Glycyl-N-methylglycine; H-Gly-Sar-OH; GLYCYL-SARCOSINE; Glycyl-sarcosin; 2-[(2-Aminoacetyl)(methyl)amino]acetic acid
EINECS	Contact for details

Quality Control

Our Glycyl-Sarcosine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While typically supplied as a research-grade material, production can be aligned with specific customer requirements for pharmaceutical or analytical reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); therefore, containers must be kept tightly sealed after use to prevent degradation from moisture absorption and exposure to light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.